Prodynorphin gene disruption increases the sensitivity to nicotine self-administration in mice
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چکیده
منابع مشابه
Prodynorphin gene disruption increases the sensitivity to nicotine self-administration in mice.
The endogenous opioid system has been reported to participate in nicotine behavioural responses. The aim of the study was to determine the contribution of the endogenous peptides derived from prodynorphin in acute and chronic nicotine responses, mainly those related to its addictive properties. Locomotion and nociception were evaluated after acute nicotine administration in prodynorphin knockou...
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ژورنال
عنوان ژورنال: The International Journal of Neuropsychopharmacology
سال: 2008
ISSN: 1461-1457,1469-5111
DOI: 10.1017/s1461145708009450